Type 2 Diabetes Reversal Possible With WWI Chemical, Study Shows

Mar 03, 2015 11:20 AM EST | By Victoria Guerra

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In the midst of the obesity epidemic crisis, many other diseases related to it are being studied and treated, including the different levels of hyperglycemia and insulin resistance in the body - now, a new study has shown that there might be a way around type 2 diabetes reversal after first experiments with rodents.

Millions of people in the United States and the whole world suffer from this disease, so the possibility of a type 2 diabetes reversal process is not only good news but it could be potentially life-saving, as it's a delicate illness that can lead to several complications that make the life of its patients fairly difficult.

According to Science Daily, the study about the type 2 diabetes reversal is called "Controlled-release mitochondrial protonophore reverses diabetes and steatohepatitis in rats" and was recently published in the journal Science, following research on Yale University.

As YaleNews reports, the scientists developed an oral treatment that's proven type 2 diabetes reversal in mice, as well as fatty liver disease. The team of researchers investigated whether an agent used for weight loss 70 years ago, in the times of World War I, could be reformulated to treat NAFLD/NASH and type 2 diabetes.

The chemical, called mitochondrial protonophore 2, 4-dinitropherol (DNP) was mixed during that time in factories with piric acid to make explosives; however, exposure to DNP caused the factory workers to lose weight and experience high temperatures.

According to Diabetes.co.uk, the use of DNP for type 2 diabetes reversal was a success, as it appeared to also reduce liver fat, inflammation, blood glucose and insulin concentration when used in levels lower than toxic.

It seems like the result is inked to the plasma concentrations, but this would require further research.

"Given these promising results in animal models of fatty live disease and type 2 diabetes we are pursuing additional preclinical safety studies to take this approach to the clinic," said Gerald Shulman to The Telegraph, giving readers hope about a possible human treatment for type 2 diabetes reversal in the future.

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